DKK2 Antikörper
Kurzübersicht für DKK2 Antikörper (ABIN7113473)
Target
Alle DKK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- dickkopf homolog 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:1000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Andere Bezeichnung
- DKK2
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Hintergrund
- Synonyms:Dickkopf 2, Dickkopf related protein 2, DKK 2, DKK2, hDkk 2 Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease(By similarity).
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Molekulargewicht
- 32 kDa
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Gen-ID
- 27123
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UniProt
- Q9UBU2
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Pathways
- WNT Signalweg
Target
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