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Diazepam Binding Inhibitor Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Diazepam Binding Inhibitor in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7113469

Kurzübersicht für Diazepam Binding Inhibitor Antikörper (ABIN7113469)

Target

Alle Diazepam Binding Inhibitor (DBI) Antikörper anzeigen
Diazepam Binding Inhibitor (DBI)

Reaktivität

  • 41
  • 15
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 45
  • 4
Kaninchen

Klonalität

  • 46
  • 3
Polyklonal

Konjugat

  • 27
  • 9
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Diazepam Binding Inhibitor Antikörper ist unkonjugiert

Applikation

  • 37
  • 28
  • 14
  • 14
  • 8
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    Diazepam Binding Inhibitor (DBI)

    Andere Bezeichnung

    DBI

    Hintergrund

    Synonyms:DBI, ACBD1, ACBP, CCK-RP, EP, acyl-CoA-binding protein Background:This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

    Molekulargewicht

    12 kDa

    Gen-ID

    1622

    UniProt

    P07108
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