Cytochrome C Antikörper
Kurzübersicht für Cytochrome C Antikörper (ABIN7113248)
Target
Alle Cytochrome C (CYCS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- Cytochrome c
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Isotyp
- IgG2a
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Applikationshinweise
- WB: 1:5000-1:30000, IHC: 1:100-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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Andere Bezeichnung
- Cytochrome c
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Hintergrund
- Synonyms:CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4 Background:Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
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Molekulargewicht
- 12 kDa
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Gen-ID
- 54205
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UniProt
- P99999
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
Target
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