CRYAB Antikörper
Kurzübersicht für CRYAB Antikörper (ABIN7113086)
Target
Alle CRYAB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- CRYAB antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- crystallin, alpha B
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- CRYAB (Crystallin, alpha B (CRYAB))
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Andere Bezeichnung
- CRYAB
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Hintergrund
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Synonyms: Alpha-crystallin B chain|Alpha(B)-crystallin|Heat shock protein beta-5 (HspB5)|Renal carcinoma antigen NY-REN-27|Rosenthal fiber component|CRYAB|CRYA2|HSPB5
Background: Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms(SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders.
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Molekulargewicht
- 20 kDa
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UniProt
- P02511
Target
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