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C4BPB Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch C4BPB in WB, IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7113013

Kurzübersicht für C4BPB Antikörper (ABIN7113013)

Target

Alle C4BPB Antikörper anzeigen
C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Reaktivität

  • 42
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 34
  • 8
Kaninchen

Klonalität

  • 35
  • 7
Polyklonal

Konjugat

  • 30
  • 5
  • 4
  • 1
  • 1
  • 1
Dieser C4BPB Antikörper ist unkonjugiert

Applikation

  • 37
  • 22
  • 15
  • 11
  • 9
  • 6
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    complement component 4 binding protein, beta

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

    Andere Bezeichnung

    C4BPB

    Hintergrund

    Synonyms:C4b binding protein beta chain, C4BP, C4BPB Background:This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

    Molekulargewicht

    40-45 kDa

    Gen-ID

    725

    UniProt

    P20851

    Pathways

    Komplementsystem
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