CHAF1A Antikörper
Kurzübersicht für CHAF1A Antikörper (ABIN7112742)
Target
Alle CHAF1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- CHAF1A antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- chromatin assembly factor 1, subunit A(p150)
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))
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Andere Bezeichnung
- CHAF1A
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Hintergrund
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Synonyms: Chromatin assembly factor 1 subunit A (CAF-1 subunit A)|Chromatin assembly factor I p150 subunit (CAF-I 150 kDa subunit, CAF-I p150, hp150)|CHAF1A|CAF|CAF1P150
Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci(By similarity).
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Molekulargewicht
- 150 kDa
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Gen-ID
- 10036
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UniProt
- Q13111
Target
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