CTNND1 Antikörper (AA 470-712)
Kurzübersicht für CTNND1 Antikörper (AA 470-712) (ABIN7112388)
Target
Alle CTNND1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 470-712
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Verwendungszweck
- CTNND1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 470-712aa
Immunogen: catenin, delta 1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
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Andere Bezeichnung
- CTNND1
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Hintergrund
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Synonyms: Catenin delta-1|Cadherin-associated Src substrate (CAS)|p120 catenin (p120(ctn))|p120(cas)|CTNND1|KIAA0384
Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway(By similarity). Associates with and regulates the cell adhesion properties of both C-, E-and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
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Molekulargewicht
- 105 kDa, 66 kDa
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UniProt
- O60716
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
Target
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