CES1 Antikörper

Produktnummer ABIN7112300

Der Kaninchen Polyklonal Anti-CES1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, CES1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für CES1 Antikörper (ABIN7112300)

Target: CES1 (Carboxylesterase 1 (CES1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CES1 Antikörper

Verwendungszweck: CES1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: carboxylesterase 1 (monocyte/macrophage serine esterase 1)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Andere Bezeichnung: CES1

Hintergrund:

Synonyms: Liver carboxylesterase 1|Acyl-coenzyme A:cholesterol acyltransferase (ACAT)|Brain carboxylesterase hBr1|Carboxylesterase 1 (CE-1, hCE-1)|Cholesteryl ester hydrolase (CEH)|Cocaine carboxylesterase|Egasyn|HMSE|Methylumbelliferyl-acetate deacetylase 1|Monocyte/macrophage serine esterase|Retinyl ester hydrolase (REH)|Serine esterase 1|Triacylglycerol hydrolase (TGH)|CES1|CES2|SES1

Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Molekulargewicht: 62 kDa

Gen-ID: 1066

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process