CHST14 Antikörper
Kurzübersicht für CHST14 Antikörper (ABIN7112278)
Target
Alle CHST14 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- CHST14 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- carbohydrate(N-acetylgalactosamine 4-0) sulfotransferase 14
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))
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Andere Bezeichnung
- CHST14
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Hintergrund
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Synonyms: Carbohydrate sulfotransferase 14|Dermatan 4-sulfotransferase 1 (D4ST-1, hD4ST1)|CHST14|D4ST1
Background: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid(IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
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Molekulargewicht
- 45-50 kDa
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Gen-ID
- 113189
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UniProt
- Q8NCH0
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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