Calsyntenin 1 Antikörper
Kurzübersicht für Calsyntenin 1 Antikörper (ABIN7112234)
Target
Alle Calsyntenin 1 (CLSTN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- calsyntenin 1
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Isotyp
- IgG
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anti-Calsyntenin 1 (CLSTN1) (AA 35-84) antibody
CLSTN1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 1-971) antibodyCLSTN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (C-Term) antibodyCLSTN1 Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 15-42), (N-Term) antibodyCLSTN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB38737 unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 29-350) antibodyCLSTN1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) antibodyKD Validated CLSTN1 Reaktivität: Human, Maus WB, IHC, IF, ICC Wirt: Kaninchen Monoclonal unconjugated Recombinant Antibody
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- Calsyntenin 1 (CLSTN1)
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Andere Bezeichnung
- CLSTN1
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Hintergrund
- Synonyms:CS1, KIAA0911 Background:Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment(AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals(By similarity).
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Molekulargewicht
- 109kd
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Gen-ID
- 22883
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UniProt
- O94985
Target
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