CAMKK2 Antikörper

Produktnummer ABIN7112196

Dieses Anti-CAMKK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CAMKK2 in WB, ELISA, IHC und IF. Geeignet für Human und Maus.

Kurzübersicht für CAMKK2 Antikörper (ABIN7112196)

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMKK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CAMKK2 Antikörper

Verwendungszweck: CAMKK2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-353

Immunogen: calcium/calmodulin-dependent protein kinase kinase 2, beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CAMKK2

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Andere Bezeichnung: CAMKK2

Hintergrund:

Synonyms: Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2, CaM-kinase kinase 2, CaMKK 2)|Calcium/calmodulin-dependent protein kinase kinase beta (CaM-KK beta, CaM-kinase kinase beta, CaMKK beta)|CAMKK2|CAMKKB|KIAA0787

Background: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.

Molekulargewicht: 55-60 kDa

Gen-ID: 10645

UniProt: Q96RR4

Pathways: AMPK Signaling