BBS9 Antikörper

Produktnummer ABIN7111939

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BBS9 in ELISA, WB, IHC, IF und IP. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für BBS9 Antikörper (ABIN7111939)

Target: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS9 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-BBS9 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Bardet-Biedl syndrome 9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:6000, IP: 1:500-1:3000, IHC: 1:50-1:500, IF: 1:50-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu BBS9

Target: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Andere Bezeichnung: BBS9

Hintergrund: Synonyms:PTHB1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

Molekulargewicht: 60 kDa

Gen-ID: 27241

UniProt: Q3SYG4

Pathways: Hedgehog Signalweg