ATG12 Antikörper
Kurzübersicht für ATG12 Antikörper (ABIN7111887)
Target
Alle ATG12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ATG12 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ATG12 autophagy related 12 homolog
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Isotyp
- IgG
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anti-Autophagy Related 12 (ATG12) (N-Term) antibody
ATG12 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Affe, Huhn, Kaninchen, Schwein, Cat, Esel, Ziege, Hamster, Schaf, Avian WB, IF Wirt: Ziege Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-30), (N-Term) antibodyATG12 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7475 unconjugated
anti-Autophagy Related 12 (ATG12) antibodyATG12 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Maus Monoclonal 43CT73-3-5-5-4 unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-74) antibodyATG12 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) (AA 101-187) antibodyATG12 Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-50) antibodyATG12 Reaktivität: Human, Maus WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) antibodyATG12 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Autophagy Related 12 (ATG12) antibodyATG12 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB3425 unconjugated Recombinant Antibody
anti-Autophagy Related 12 (ATG12) (AA 8-38), (N-Term) antibodyATG12 Reaktivität: Human, Maus IF Wirt: Kaninchen Polyclonal RB2793 unconjugated
anti-Autophagy Related 12 (ATG12) antibodyATG12 Reaktivität: Human WB Wirt: Maus Monoclonal 43CT73-3-5-5-4 unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:2000 , IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ATG12 (Autophagy Related 12 (ATG12))
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Andere Bezeichnung
- ATG12
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Hintergrund
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Synonyms: Ubiquitin-like protein ATG12|Autophagy-related protein 12 (APG12-like)|ATG12|APG12|APG12L
Background: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.
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Molekulargewicht
- 48-50 kDa
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Gen-ID
- 9140
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UniProt
- O94817
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Pathways
- Autophagie
Target
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