Der Kaninchen Polyklonal Anti-ABCC1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, ABCC1 in Proben von Human, Maus und Ratte zu detektieren.
ABCC1
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
1G8
unconjugated
Applikationshinweise
WB 1:500-1:1000, IHC 1:50-1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
ABCC1
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
Andere Bezeichnung
ABCC1
Hintergrund
Synonyms:ABC29, ABCC, ABCC1, ATP-binding cassette sub-family C member 1, ATP-binding cassette, sub-family C(CFTR/MRP), member 1, EC 3.6.3, EC 3.6.3.44, GS-X, Leukotriene C(4) transporter, LTC4 transporter, MRP1,multidrug resistance associated protein 1, multidrug resistance protein, multidrug resistance-associated protein 1, multiple drug resistance protein 1, multiple drug resistance-associated protein Background:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.