Liver Arginase Antikörper

Produktnummer ABIN7111709

Der Kaninchen Polyklonal Anti-Liver Arginase-Antikörper wurde für WB, ELISA, IHC, FACS, IF und IP validiert. Er ist geeignet, Liver Arginase in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Liver Arginase Antikörper (ABIN7111709)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Liver Arginase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-Liver Arginase Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: arginase, liver

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: liver Arginase

Hintergrund: Synonyms:ARG1, Arginase 1, liver Arginase, Liver type arginase Background:Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemicalmarkerof hepatocellular differentiation in fine needle aspiration cytology and a markerof hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

Molekulargewicht: 35 kDa

Gen-ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin