AKR7A2 Antikörper

Produktnummer ABIN7111415

Der Kaninchen-Polyklonal Anti-AKR7A2-Antikörper wurde für WB, IHC, ELISA und IF validiert. Er ist geeignet zum Nachweis von AKR7A2 in Proben aus Human und Maus. }

Kurzübersicht für AKR7A2 Antikörper (ABIN7111415)

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR7A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-AKR7A2 Antikörper

Verwendungszweck: AKR7A2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu AKR7A2

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Andere Bezeichnung: AKR7A2

Hintergrund:

Synonyms: Aflatoxin B1 aldehyde reductase member 2|AFB1 aldehyde reductase 1 (AFB1-AR 1)|Aldoketoreductase 7|Succinic semialdehyde reductase (SSA reductase)|AKR7A2|AFAR|AFAR1|AKR7

Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 40 kDa

Gen-ID: 8574

UniProt: O43488