AFF4 Antikörper

Produktnummer ABIN7111407

Dieses Anti-AFF4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AFF4 in WB, ELISA und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für AFF4 Antikörper (ABIN7111407)

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-AFF4 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: AF4/FMR2 family, member 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu AFF4

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Andere Bezeichnung: AFF4

Hintergrund: Synonyms:AF4/FMR2 family member 4, AF4/FMR2 family, member 4, AF5Q31, AFF4, MCEF, Protein AF 5q31 Background:Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Molekulargewicht: 150 kDa

Gen-ID: 27125

UniProt: Q9UHB7