ADAR Antikörper

Produktnummer ABIN7111327

Produktdetails anti-ADAR Antikörper

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: adenosine deaminase, RNA-specific

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:50-1:200, IP: 1:200-1:1000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Andere Bezeichnung: ADAR1 (ADAR Produkte)

Synonyme: red1 antikoerper, drada antikoerper, wu:fc22a02 antikoerper, adar1 antikoerper, dsRAD antikoerper, dsRAD-1 antikoerper, ADAR antikoerper, ADAR1 antikoerper, CG12598 antikoerper, Dmel\\CG12598 antikoerper, EG:BACN35H14.1 antikoerper, adar antikoerper, adr antikoerper, cg12598 antikoerper, dADAR antikoerper, dAdar antikoerper, hypnos-2 antikoerper, NV18763 antikoerper, AGS6 antikoerper, DRADA antikoerper, DSH antikoerper, DSRAD antikoerper, G1P1 antikoerper, IFI-4 antikoerper, IFI4 antikoerper, K88DSRBP antikoerper, P136 antikoerper, AV242451 antikoerper, Adar1 antikoerper, mZaADAR antikoerper, adenosine deaminase, RNA-specific antikoerper, adenosine deaminase, RNA-specific S homeolog antikoerper, adenosine deaminase, RNA specific antikoerper, Adenosine deaminase acting on RNA antikoerper, adenosine deaminase acting on RNA antikoerper, double-stranded RNA-specific editase 1 antikoerper, adar antikoerper, adar.S antikoerper, ADAR antikoerper, Adar antikoerper, CpipJ_CPIJ011849 antikoerper, LOC100114127 antikoerper

Hintergrund: Synonyms:ADAR, ADAR1, adenosine deaminase, RNA, DRADA, DSH, DSRAD, G1P1, IFI 4, IFI4, Interferon inducible protein 4, K88dsRBP, p136 Background:ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).

Molekulargewicht: 110 kDa

Gen-ID: 103

UniProt: P55265

Pathways: Protein targeting to Nucleus