XRN2 Antikörper
Kurzübersicht für XRN2 Antikörper (ABIN7111135)
Target
Alle XRN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- XRN2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- 5'-3' exoribonuclease 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:200-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- XRN2 (5'-3' Exoribonuclease 2 (XRN2))
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Andere Bezeichnung
- XRN2
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Hintergrund
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Synonyms: 5'-3' exoribonuclease 2|DHM1-like protein (DHP protein)|XRN2
Background: Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224).
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Molekulargewicht
- 108 kDa
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Gen-ID
- 22803
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UniProt
- Q9H0D6
Target
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