XRN2 Antikörper

Produktnummer ABIN6266072

Produktdetails anti-XRN2 Antikörper

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Reaktivität: Human, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: XRN2 Antibody detects endogenous levels of XRN2

Kreuzreaktivität: Human, Affe, Maus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human XRN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu XRN2

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Andere Bezeichnung: XRN2 (XRN2 Produkte)

Synonyme: zgc:55717 antikoerper, wu:fb38g12 antikoerper, wu:fj53d06 antikoerper, AO090012000503 antikoerper, DKFZp459J063 antikoerper, AtXRN2 antikoerper, EXORIBONUCLEASE 2 antikoerper, K16E1.2 antikoerper, K16E1_2 antikoerper, exoribonuclease 2 antikoerper, 5'-3' exoribonuclease 2 antikoerper, 5'-3' exoribonuclease 2, putative antikoerper, 5'-3' exoribonuclease 2 S homeolog antikoerper, exoribonuclease 2 antikoerper, xrn2 antikoerper, XRN2 antikoerper, TA11675 antikoerper, LELG_04162 antikoerper, AOR_1_874194 antikoerper, PTRG_01514 antikoerper, PTRG_10866 antikoerper, Tsp_08094 antikoerper, xrn2.S antikoerper, Xrn2 antikoerper

Hintergrund:

Description: Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).

Gene: XRN2

Molekulargewicht: 108kDa

Gen-ID: 22803

UniProt: Q9H0D6