CD27 Antikörper (AA 20-191) (Biotin)

Produktnummer ABIN7093003

Der Kaninchen Monoklonal anti-CD27 Antikörper wird verwendet zum Nachweis von CD27 in Proben von Human. Er wurde validiert für FACS und ELISA.

Kurzübersicht für CD27 Antikörper (AA 20-191) (Biotin) (ABIN7093003)

Target: CD27 (CD27 Molecule (CD27))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD27 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), ELISA

Klon: DM57

Produktdetails anti-CD27 Antikörper (Biotin)

Bindungsspezifität: AA 20-191

Verwendungszweck: Biotinylated Anti-CD27 antibody(DM57), Rabbit mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human CD27 (Ala20-Arg191) (ABIN6961160) produced by using human HEK293 cells

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:5000-10000, Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27

Hintergrund: Synonyms:CD27, TNFRSF7, S152, T14, Tp55
Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Molekulargewicht: 29 kDa

Gen-ID: 939

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints