ACE2 Antikörper (AA 18-740) (Biotin)

Produktnummer ABIN7092996

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch ACE2 in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ACE2 Antikörper (AA 18-740) (Biotin) (ABIN7092996)

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ACE2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Flow Cytometry (FACS)

Klon: DM47

Produktdetails anti-ACE2 Antikörper (Biotin)

Bindungsspezifität: AA 18-740

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human  ACE2(Gln18-Ser740) (ABIN6961130) produced by using human HEK293 cells

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1/5000-10000,Flow Cyt  1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: 50 % Glycerol, PBS, pH 7.4, 0.1 % BSA,0.1 % Procline 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu ACE2

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Andere Bezeichnung: ACE2

Hintergrund: Synonyms:ACE-2, ACEH, ACE2
Description:The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Molekulargewicht: 92.4 kDa

Gen-ID: 59272

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour