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MICA Antikörper (AA 24-307)

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch MICA in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7092957

Kurzübersicht für MICA Antikörper (AA 24-307) (ABIN7092957)

Target

Alle MICA Antikörper anzeigen
MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

Reaktivität

  • 80
  • 18
  • 14
  • 11
  • 7
  • 5
  • 2
  • 1
Human

Wirt

  • 43
  • 35
  • 4
Kaninchen

Klonalität

  • 41
  • 38
  • 2
Monoklonal

Konjugat

  • 53
  • 8
  • 7
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MICA Antikörper ist unkonjugiert

Applikation

  • 51
  • 41
  • 37
  • 22
  • 21
  • 14
  • 9
  • 8
  • 6
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Flow Cytometry (FACS)

Klon

DM157
  • Bindungsspezifität

    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-307

    Aufreinigung

    Purified from cell culture supernatant by affinity chromatography

    Immunogen

    Recombinant human MICA(Glu24-Trp307) (ABIN6964102) produced by using human HEK293 cells

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1/5000-10000,Flow Cyt 1/100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute with deionized water

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

    Andere Bezeichnung

    MICA

    Hintergrund

    Synonyms:MIC-A, PERB11.1
    Description:This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]

    Molekulargewicht

    42.9KDa

    Pathways

    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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