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MICA Antikörper (AA 24-307)

MICA Reaktivität: Human ELISA, FACS Wirt: Kaninchen Monoclonal DM157 unconjugated
Produktnummer ABIN7092957
  • Target Alle MICA Antikörper anzeigen
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Bindungsspezifität
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-307
    Reaktivität
    • 80
    • 18
    • 14
    • 11
    • 7
    • 5
    • 2
    • 1
    Human
    Wirt
    • 43
    • 35
    • 4
    Kaninchen
    Klonalität
    • 41
    • 38
    • 2
    Monoklonal
    Konjugat
    • 53
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MICA Antikörper ist unkonjugiert
    Applikation
    • 51
    • 41
    • 37
    • 22
    • 21
    • 14
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Aufreinigung
    Purified from cell culture supernatant by affinity chromatography
    Immunogen
    Recombinant human MICA(Glu24-Trp307) (ABIN6964102) produced by using human HEK293 cells
    Klon
    DM157
    Isotyp
    IgG
    Top Product
    Discover our top product MICA Primärantikörper
  • Applikationshinweise
    ELISA 1/5000-10000,Flow Cyt 1/100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Andere Bezeichnung
    MICA (MICA Produkte)
    Hintergrund
    Synonyms:MIC-A, PERB11.1
    Description:This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
    Molekulargewicht
    42.9KDa
    Pathways
    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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