CD86 Antikörper (AA 26-247)

Produktnummer ABIN7092885

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch CD86 in FACS und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD86 Antikörper (AA 26-247) (ABIN7092885)

Target: CD86

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Klon: DM84

Produktdetails anti-CD86 Antikörper

Bindungsspezifität: AA 26-247

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human B7-2 (Leu26-Pro247) (ABIN6961107) produced by using human HEK293 cells

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1/5000-10000,Flow Cyt  1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu CD86

Target: CD86

Andere Bezeichnung: B7-2

Hintergrund: Synonyms:CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Description:This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Molekulargewicht: 37.7kDa

Gen-ID: 942

UniProt: P42081

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation