tau Antikörper (pThr217) (Biotin)

Produktnummer ABIN7091996

Dieses Anti-tau-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von tau in WB und IHC (p). Geeignet für Human.

Kurzübersicht für tau Antikörper (pThr217) (Biotin) (ABIN7091996)

Target: tau (tau Protein)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser tau Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-tau Antikörper (Biotin)

Bindungsspezifität: pThr217

Kreuzreaktivität: Human

Aufreinigung: affinity Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Tau around the phosphorylation site of Thr4217)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu tau

Target: tau (tau Protein)

Andere Bezeichnung: Tau

Hintergrund:

Synonyms: Tau(Phospho-Thr217), MAPT(phospho T217),Tau(Phospho-Thr217), MAPT, Microtuble-associted protein Tau, AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPTL, MGC134287, MGC138549, MGC156663, Microtubule associated protein tau isoform 4, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PHF-tau, PPND, pTau, RNPTAU, Tauopathy and respiratory failure, included, TAU_HUMAN.

Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Gen-ID: 4137

UniProt: P10636