USP2 Antikörper (AA 1-258)

Produktnummer ABIN7091801

Dieses Anti-USP2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von USP2 in WB. Geeignet für Human.

Kurzübersicht für USP2 Antikörper (AA 1-258) (ABIN7091801)

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser USP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1738CT331-50-87

Produktdetails anti-USP2 Antikörper

Bindungsspezifität: AA 1-258

Kreuzreaktivität: Green Monkey, Human

Aufreinigung: Purified by Protein G.

Immunogen: Recombinant human USP2 between 1-258 amino acids.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu USP2

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Andere Bezeichnung: USP2

Hintergrund:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 2, 3.4.19.12, 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease 2, USP2, UBP41

Background: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Gen-ID: 9099

UniProt: O75604