TSC1 Antikörper
Kurzübersicht für TSC1 Antikörper (ABIN7091774)
Target
Alle TSC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Homologie
- Human
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Immunogen
- Recombinant human TSC1 (Fragment) (His-tagged).
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Isotyp
- IgG2b
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Applikationshinweise
- WB 1:300-5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Andere Bezeichnung
- TSC1
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Hintergrund
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Synonyms: LAM, Hamartin, Tuberous sclerosis 1 protein, TSC1_HUMAN, KIAA0243, TSC, Tuberous sclerosis 1.
Background: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
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Gen-ID
- 7248
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UniProt
- Q92574
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Pathways
- RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
Target
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