NRF1 Antikörper

Produktnummer ABIN7091482

Der Maus Monoklonal Anti-NRF1-Antikörper wurde für WB, IF und ICC validiert. Er ist geeignet, NRF1 in Proben von Human zu detektieren.

Kurzübersicht für NRF1 Antikörper (ABIN7091482)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: A11D10

Produktdetails anti-NRF1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human NRF1

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF()
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Andere Bezeichnung: NRF1

Hintergrund:

Synonyms: erythroid derived 2, like 1, Locus control region factor 1, Locus control region-factor 1, NF-E2-related factor 1, NF2L1_HUMAN, NFE2 related factor 1, NFE2-related factor 1, NFE2L1, NRF-1, NRF 1, Nuclear factor, Nuclear factor erythroid 2-related factor 1, Nuclear factor erythroid derived 2 like 1, TCF-11, TCF11, Transcription factor 11, Transcription factor HBZ17, Transcription factor LCR F1, Transcription factor LCR-F1.

Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]

Gen-ID: 4899

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha