Glypican 3 Antikörper

Produktnummer ABIN7091174

Dieses Anti-Glypican 3-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Glypican 3 in IF, FACS, WB und ICC. Geeignet für Human.

Kurzübersicht für Glypican 3 Antikörper (ABIN7091174)

Target: Glypican 3 (GPC3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Glypican 3 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunocytochemistry (ICC)

Klon: G8A2

Produktdetails anti-Glypican 3 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glypican 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IF()
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Glypican 3

Target: Glypican 3 (GPC3)

Andere Bezeichnung: Glypican 3

Hintergrund:

Synonyms: GPC3, glypican3, glypican-3, Intestinal protein OCI-5, GTR2-2, MXR7.Intestinal protein OCI-5, GPC3_HUMAN.

Background: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Gen-ID: 2719

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process