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DKK2 Antikörper

DKK2 Reaktivität: Human WB Wirt: Maus Monoclonal J3F5 unconjugated
Produktnummer ABIN7091038
  • Target Alle DKK2 Antikörper anzeigen
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Reaktivität
    • 51
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 3
    • 1
    Maus
    Klonalität
    • 48
    • 3
    Monoklonal
    Konjugat
    • 27
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DKK2 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 26
    • 24
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Homologie
    Human,Mouse
    Immunogen
    Recombinant human DKK2.
    Klon
    J3F5
    Top Product
    Discover our top product DKK2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Andere Bezeichnung
    DKK2 (DKK2 Produkte)
    Hintergrund

    Synonyms: Dickkopf 2, Dickkopf gene 2, Dickkopf homolog 2, Dickkopf related protein 2, Dickkopf-2, Dickkopf-related protein 2, Dickkopf2, DKK 2, Dkk-2, DKK2_HUMAN, hDkk 2, hDkk-2, hDkk2.

    Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

    Gen-ID
    27123
    UniProt
    Q9UBU2
    Pathways
    WNT Signalweg
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