DKK2 Antikörper
-
- Target Alle DKK2 Antikörper anzeigen
- DKK2 (Dickkopf 2 Homolog (DKK2))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser DKK2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Homologie
- Human,Mouse
- Immunogen
- Recombinant human DKK2.
- Klon
- J3F5
- Top Product
- Discover our top product DKK2 Primärantikörper
-
-
- Applikationshinweise
- WB 1:300-5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- DKK2 (Dickkopf 2 Homolog (DKK2))
- Andere Bezeichnung
- DKK2 (DKK2 Produkte)
- Hintergrund
-
Synonyms: Dickkopf 2, Dickkopf gene 2, Dickkopf homolog 2, Dickkopf related protein 2, Dickkopf-2, Dickkopf-related protein 2, Dickkopf2, DKK 2, Dkk-2, DKK2_HUMAN, hDkk 2, hDkk-2, hDkk2.
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
- Gen-ID
- 27123
- UniProt
- Q9UBU2
- Pathways
- WNT Signalweg
-