CEACAM1 Antikörper

Produktnummer ABIN7090813

Der Kaninchen Monoklonal Anti-CEACAM1-Antikörper wurde für IHC (p) validiert. Er ist geeignet, CEACAM1 in Proben von Human zu detektieren.

Kurzübersicht für CEACAM1 Antikörper (ABIN7090813)

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: A10D5

Produktdetails anti-CEACAM1 Antikörper

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD66a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Andere Bezeichnung: CD66a

Hintergrund:

Synonyms: CEACAM1, carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1 precursor, Antigen CD66, BGP, BGP 1, BGP I, BGP1,BGPI, Biliary glycoprotein 1, Biliary glycoprotein adhesion molecule, Biliary glycoprotein, Carcinoembryonic antigen related cell adhesion molecule 1, CD66 antigen, CD66a antigen, CEACAM 1, bb-1, C-CAM, Cc1, Cea-1, Cea-7, Cea1, Cea7, Hv-2, Hv2, mCEA1, Mhv-1, MHVR, MHVR1, mmCGM1, mmCGM1a, mmCGM2, CEAM1_HUMAN.

Background: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010].

Gen-ID: 634

UniProt: P13688