Caldesmon Antikörper

Produktnummer ABIN7090803

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Caldesmon in WB, IF, IHC (p) und ICC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Caldesmon Antikörper (ABIN7090803)

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Caldesmon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Klon: C2D4

Produktdetails anti-Caldesmon Antikörper

Kreuzreaktivität: Maus

Homologie: Human,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Caldesmon

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF()
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Andere Bezeichnung: Caldesmon

Hintergrund:

Synonyms: CAD, CALD 1, CALD1, Caldesmon 1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, aldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, Caldesmon1, CDM, H CAD, HCAD, L CAD, LCAD, MGC21352, NAG22, Caldesmon-Pan, CALD1_HUMAN.

Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008].

Gen-ID: 800

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction