UGT2B4 Antikörper (AA 111-210) (Cy3)

Produktnummer ABIN705509

Der Kaninchen Polyklonal anti-UGT2B4 Antikörper wird verwendet zum Nachweis von UGT2B4 in Proben von Human. Er wurde validiert für WB, IF (cc) und IF (p).

Kurzübersicht für UGT2B4 Antikörper (AA 111-210) (Cy3) (ABIN705509)

Target: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT2B4 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-UGT2B4 Antikörper (Cy3)

Bindungsspezifität: AA 111-210

Homologie: Human,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UGT2B4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UGT2B4

Target: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Andere Bezeichnung: UGT2B4

Hintergrund:

Synonyms: HLUG25, Hyodeoxycholic acid, UDP glucuronosyltransferase 2 family polypeptide B4, UDP glucuronosyltransferase 2B4 precursor, UDP glucuronyltransferase family 2 beta 4, UDP glycosyltransferase 2 family polypeptide B4, UDP glycosyltransferase, UDPGT, UDPGTh 1, UDPGTh1, UGT2B11, UGT2B4, UD2B4_HUMAN.

Background: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.

Gen-ID: 7363

Pathways: Steroid Hormone Biosynthesis