UGT2B4 Antikörper (N-Term)
Kurzübersicht für UGT2B4 Antikörper (N-Term) (ABIN2783820)
Target
Alle UGT2B4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- UGT2B4 Antibody - N-terminal region
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Sequenz
- NIKTILDELV QRGHEVTVLA SSASISFDPN SPSTLKFEVY PVSLTKTEFE
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against UGT2B4. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human UGT2B4
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49624-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))
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Andere Bezeichnung
- UGT2B4
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Hintergrund
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Background Information: UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Gene Name: UDP glucuronosyltransferase 2 family, polypeptide B4
Alternative Symbols: HLUG25, UDPGTH1, UGT2B11, UDPGT2B4, UDPGTh-1
Protein Name: UDP-glucuronosyltransferase 2B4
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Molekulargewicht
- 60kDa
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Gen-ID
- 7363
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NCBI Accession
- NP_066962
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UniProt
- P06133
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Pathways
- Steroid Hormone Biosynthesis
Target
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