Myeloperoxidase Antikörper (FITC)

Produktnummer ABIN7077551

Der Maus Monoklonal Anti-Myeloperoxidase-Antikörper wurde für FACS validiert. Er ist geeignet, Myeloperoxidase in Proben von Human zu detektieren.

Kurzübersicht für Myeloperoxidase Antikörper (FITC) (ABIN7077551)

Target: Myeloperoxidase (MPO)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Myeloperoxidase Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: 8-9

Produktdetails anti-Myeloperoxidase Antikörper (FITC)

Verwendungszweck: MPO FITC Antibody

Produktmerkmale: The clone 8/9, a mouse monoclonal antibody selectively binds with myeloperoxidase (MPO), a glycoprotein present in the granules of myeloid cells. MPO is critical for an optimal oxygen-dependent microbicidal activity of myeloid cells. The MPO generally appears in the myeloblast stage of myeloid cell differentiation. It is the most common functional protein of myeloid cells and is involved in the process of inflammatory immune responses mediated by myeloid cells. The primary translation product of MPO undergoes glycosylation with the production of 89 kDa heme-free apopro-MPO form followed by incorporation of heme and conversion into the enzymatically active pro-MPO form. Subsequently, pro-MPO becomes targeted to azurophil granules where final processing occurs to produce mature dimeric MPO consisting of the 59-64 kDa MPO alpha-chain and the 14 kDa MPO beta-chain. MPO gene expression may serve as an additional marker for subclassification of acute leukemias and may be used to identify leukemic cells arrested at an early stage of the myeloid differentiation pathway.

Aufreinigung: Purified

Reinheit: >95 %

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu Myeloperoxidase

Target: Myeloperoxidase (MPO)

Andere Bezeichnung: MPO

Gen-ID: 4353

UniProt: P05164

Pathways: Chromatin Binding