TSC1 Antikörper (AA 131-230) (Biotin)
Kurzübersicht für TSC1 Antikörper (AA 131-230) (Biotin) (ABIN704848)
Target
Alle TSC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 131-230
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Kreuzreaktivität
- Schaf
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Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Hamartin
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Isotyp
- IgG
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anti-Tuberous Sclerosis 1 (TSC1) (AA 550-650) antibody
TSC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 3A2 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibodyTSC1 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 5A8 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) antibodyTSC1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB11648 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 101-344) antibodyTSC1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pSer505) antibodyTSC1 Reaktivität: Human, Maus, Schaf ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pThr416) antibodyTSC1 Reaktivität: Maus DB Wirt: Kaninchen Polyclonal RB42189 unconjugated
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Applikationshinweise
- WB 1:300-5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Andere Bezeichnung
- Hamartin/TSC1
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Hintergrund
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Synonyms: LAM, TSC1, Tuberous sclerosis 1 protein, TSC1_HUMAN.
Background: Hamartin, or TSC1, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1. It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway. TSC1 interacts with tuberin m(TSC2), which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins. The Hamartin/Tuberin complex has been shown to inhibit mTor. Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, suggesting a role for TSC proteins in modulation of cell adhesion and morphology.
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Gen-ID
- 7248
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UniProt
- Q92574
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Pathways
- RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
Target
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