CD21 Antikörper (FITC)

Produktnummer ABIN7076447

Dieses Anti-CD21-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD21 in FACS. Geeignet für Human.

Kurzübersicht für CD21 Antikörper (FITC) (ABIN7076447)

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD21 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade (Analyte)

Klon: HB5

Produktdetails anti-CD21 Antikörper (FITC)

Verwendungszweck: CD21 FITC Antibody

Produktmerkmale: The mouse monoclonal antibody produced by clone HB5 binds to complement receptor 2 (CR2), known as CD21, a 145 kDa glycoprotein of the complement control protein family. It is a receptor for the complement components C3d and C3g and, under pathological circumstances, for the Epstein-Barr virus (EBV). As complement breakdown fragments remain bound to the agent initiating the complement activation in the first place, CD21 plays an important role in the uptake of immunocomplexes. In addition, it plays a role in B cell development and activation as well as memory B cell survival. Thus, it is a key component in developing and maintaining humoral immune response to T-dependent antigens. CD21 associates with CD19, CD81 and the B cell receptor. The cell surface marker CD21 is expressed on mature B cells and follicular dendritic cells. It is used as a cell marker for the phenotyping of leukemias.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human complement receptor 2 (CR2)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu CD21

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Andere Bezeichnung: CD21

Gen-ID: 1380

UniProt: P20023

Pathways: Komplementsystem