Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ube3a Antikörper

ube3a Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7076104
  • Target Alle ube3a Antikörper anzeigen
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Reaktivität
    • 52
    • 12
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 48
    • 4
    Kaninchen
    Klonalität
    • 47
    • 5
    Polyklonal
    Konjugat
    • 29
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ube3a Antikörper ist unkonjugiert
    Applikation
    • 28
    • 17
    • 16
    • 13
    • 13
    • 10
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse UBE3A
    Top Product
    Discover our top product ube3a Primärantikörper
  • Applikationshinweise
    IHC/IF (M,R) 1:1000-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Andere Bezeichnung
    UBE3A (ube3a Produkte)
    Hintergrund
    UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. UBE3A also plays an important role in the regulation of the circadian clock. Defects in UBE3A are a cause of Angelman syndrome (AS).
    Gen-ID
    22215
    NCBI Accession
    NP_035798
    UniProt
    O08759
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
Sie sind hier:
Kundenservice