TAL1 Antikörper
Kurzübersicht für TAL1 Antikörper (ABIN7075819)
Target
Alle TAL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse Tal1
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anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibody
TAL1 Reaktivität: Human, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein, Affe, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 Reaktivität: Human WB, FACS, IF Wirt: Maus Monoclonal 4G10 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 1-114) antibodyTAL1 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 154-188) antibodyTAL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB50954 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 68-97) antibodyTAL1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15312 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 236-285) antibodyTAL1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Affe, Fledermaus, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibodyTAL1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (acLys221), (acLys222), (acLys36), (acLys37) antibodyTAL1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC/IF (R) 1:800-1:1500/1:400-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
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Andere Bezeichnung
- Tal1
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Hintergrund
- Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase alpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
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Gen-ID
- 21349
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NCBI Accession
- NP_001274317
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UniProt
- P22091
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Pathways
- Stem Cell Maintenance
Target
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