TAL1 Antikörper (T-Cell Acute Lymphocytic Leukemia 1) (N-Term)

Details for Product anti-TAL1 Antibody No. ABIN2777291, Anbieter: Anmelden zum Anzeigen
Antigen
  • SCL/tal-1
  • Scl
  • bHLHa17
  • tal-1
  • SCL
  • TCL5
  • scl
  • tcl5
  • SCL-alpha
  • SCL-beta
  • scl/tal1
  • zgc:85605
  • T cell acute lymphocytic leukemia 1
  • TAL bHLH transcription factor 1, erythroid differentiation factor
  • T-cell acute lymphocytic leukemia 1 S homeolog
  • T-cell acute lymphocytic leukemia 1
  • Tal1
  • TAL1
  • tal1.S
  • tal1
Epitop
N-Term
18
18
15
13
7
6
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
208
48
31
21
11
9
8
8
6
5
4
4
3
2
Wirt
Kaninchen
123
111
Klonalität
Polyklonal
Konjugat
Dieser TAL1 Antikörper ist unkonjugiert
11
11
11
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
154
71
69
54
37
33
18
13
12
7
3
3
2
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TAL1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984757.
Sequenz TERPPSEAAR SDPQLEGRDA AEASMAPPHL VLLNGVAKET SRAAAAEPPV
Homologie Cow: 85%, Dog: 85%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 85%
Produktmerkmale This is a rabbit polyclonal antibody against TAL1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere TAL1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung TAL1 (TAL1 Antibody Abstract)
Hintergrund TAL1 is implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. It also serves as a positive regulator of erythroid differentiation
Alias Symbols: SCL, TCL5, tal-1, bHLHa17
Protein Interaction Partner: ELSPBP1, SIN3A, KAT2B, EP300, HOXB9, DRG1, CHD3, ZHX1, STUB1, UBC, RB1, SSBP2, SSBP3, RCOR1, KDM1A, LDB1, TCF12, TCF3, RBBP7, LYL1, HDAC2, HDAC1, CHD4, CBFA2T3, RUNX1, SUPT16H, TAL1, CDK9, TRIM33, SUV39H1, SATB1, TRIM27, NCAPG2, MAPK3, SP1, LMO1, LMO2, GA
Protein Size: 331
Molekulargewicht 34 kDa
Gen-ID 6886
NCBI Accession NM_003189, NP_003180
UniProt P17542
Pathways Stem Cell Maintenance
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 331 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibody (ABIN2777291) Host: Rabbit Target Name: TAL1 Sample Type: Human Fetal Liver Antibody Dilution: 1.0u...
Western Blotting (WB) image for anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibody (ABIN2777291) WB Suggested Anti-TAL1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive ...
Produkt verwendet in: Hosur, Cox, Burzenski, Riding, Alley, Lyons, Kavirayani, Martin, Cox, Johnson, Shultz: "Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice." in: PLoS ONE, Vol. 8, Issue 1, pp. e53426, 2013 (PubMed).

Allgemeine Veröffentlichungen Zhang, Swanson: "V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies." in: The Journal of biological chemistry, Vol. 283, Issue 11, pp. 6717-27, 2008 (PubMed).

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