TAL1 Antikörper
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- Target Alle TAL1 Antikörper anzeigen
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TAL1 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse Tal1
- Top Product
- Discover our top product TAL1 Primärantikörper
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anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibody
TAL1 Reaktivität: Human, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein, Affe, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 Reaktivität: Human WB, FACS, IF Wirt: Maus Monoclonal 4G10 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 1-114) antibodyTAL1 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 154-188) antibodyTAL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB50954 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 68-97) antibodyTAL1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15312 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 236-285) antibodyTAL1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Affe, Fledermaus, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibodyTAL1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (acLys221), (acLys222), (acLys36), (acLys37) antibodyTAL1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC/IF (R) 1:800-1:1500/1:400-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
- Andere Bezeichnung
- Tal1 (TAL1 Produkte)
- Synonyme
- SCL/tal-1 antikoerper, Scl antikoerper, bHLHa17 antikoerper, tal-1 antikoerper, SCL antikoerper, TCL5 antikoerper, scl antikoerper, tcl5 antikoerper, SCL-alpha antikoerper, SCL-beta antikoerper, scl/tal1 antikoerper, zgc:85605 antikoerper, T cell acute lymphocytic leukemia 1 antikoerper, TAL bHLH transcription factor 1, erythroid differentiation factor antikoerper, T-cell acute lymphocytic leukemia 1 S homeolog antikoerper, T-cell acute lymphocytic leukemia 1 antikoerper, Tal1 antikoerper, TAL1 antikoerper, tal1.S antikoerper, tal1 antikoerper
- Hintergrund
- Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase alpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
- Gen-ID
- 21349
- NCBI Accession
- NP_001274317
- UniProt
- P22091
- Pathways
- Stem Cell Maintenance
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