SAV1 Antikörper

Produktnummer ABIN7075505

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SAV1 in IHC und IF. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für SAV1 Antikörper (ABIN7075505)

Target: SAV1 (Salvador Homolog 1 (SAV1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAV1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SAV1 Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse SAV1

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:200-1:1400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SAV1

Target: SAV1 (Salvador Homolog 1 (SAV1))

Andere Bezeichnung: SAV1

Hintergrund: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

Gen-ID: 64010

NCBI Accession: NP_071311

UniProt: Q8VEB2

Pathways: Stem Cell Maintenance