PPP4R2 Antikörper
Kurzübersicht für PPP4R2 Antikörper (ABIN7075284)
Target
Alle PPP4R2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse PPP4R2
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Applikationshinweise
- IHC/IF (M,R) 1:1000-1:4000/1:1000-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
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Andere Bezeichnung
- PPP4R2
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Hintergrund
- Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair.
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Gen-ID
- 232314
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NCBI Accession
- NP_891984
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UniProt
- Q0VGB7
Target
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