PPP4R2 Antikörper (AA 228-254)

Produktnummer ABIN1538128

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PPP4R2 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PPP4R2 Antikörper (AA 228-254) (ABIN1538128)

Target: PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP4R2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37606

Produktdetails anti-PPP4R2 Antikörper

Bindungsspezifität: AA 228-254

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPP4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PPP4R2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu PPP4R2

Target: PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

Andere Bezeichnung: PPP4R2

Hintergrund: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Molekulargewicht: 46898

Gen-ID: 151987

NCBI Accession: NP_777567

UniProt: Q9NY27