O3FAR1 Antikörper

Produktnummer ABIN7074942

Der Kaninchen Polyklonal anti-O3FAR1 Antikörper wird verwendet zum Nachweis von O3FAR1 in Proben von Maus und Ratte. Er wurde validiert für IHC und IF.

Kurzübersicht für O3FAR1 Antikörper (ABIN7074942)

Target: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser O3FAR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-O3FAR1 Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse GPR120

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:1000-1:2000/1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu O3FAR1

Target: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Andere Bezeichnung: GPCR GPR120

Hintergrund: GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.

Gen-ID: 107221

NCBI Accession: NP_861413

UniProt: Q7TMA4

Pathways: Hormone Transport