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MPL Antikörper

MPL Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074718
  • Target Alle MPL Antikörper anzeigen
    MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))
    Reaktivität
    • 58
    • 26
    • 22
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 52
    • 8
    Kaninchen
    Klonalität
    • 53
    • 7
    Polyklonal
    Konjugat
    • 20
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser MPL Antikörper ist unkonjugiert
    Applikation
    • 40
    • 37
    • 16
    • 13
    • 13
    • 9
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse TPOR
    Top Product
    Discover our top product MPL Primärantikörper
  • Applikationshinweise
    IHC/IF (M,R) 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))
    Andere Bezeichnung
    TPOR/MPL (MPL Produkte)
    Synonyme
    C-MPL antikoerper, CD110 antikoerper, MPLV antikoerper, THCYT2 antikoerper, TPOR antikoerper, TPO-R antikoerper, c-mpl antikoerper, c-mpl-I antikoerper, c-mpl-II antikoerper, hlb219 antikoerper, MPL antikoerper, mpll antikoerper, tpor antikoerper, tpor.b antikoerper, MPL proto-oncogene, thrombopoietin receptor antikoerper, myeloproliferative leukemia virus oncogene antikoerper, MPL antikoerper, Mpl antikoerper, mpl antikoerper
    Hintergrund
    The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.
    Gen-ID
    17480
    NCBI Accession
    NP_001116421
    UniProt
    Q08351
    Pathways
    JAK-STAT Signalweg
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