Der Kaninchen Polyklonal Anti-Kallikrein 7-Antikörper wurde für IHC und IF validiert. Er ist geeignet, Kallikrein 7 in Proben von Ratte und Maus zu detektieren.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
Kallikrein 7 (KLK7)
Andere Bezeichnung
Kallikrein 7/KLK7
Hintergrund
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.