IL-34 Antikörper

Produktnummer ABIN7074359

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL-34 in IHC und IF. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für IL-34 Antikörper (ABIN7074359)

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-34 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-IL-34 Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse IL-34

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:500-1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu IL-34

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Andere Bezeichnung: IL-34

Hintergrund: IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.

Gen-ID: 76527

NCBI Accession: NP_001128572

UniProt: Q8R1R4

Pathways: RTK Signalweg