HIF3A Antikörper

Produktnummer ABIN7074273

Produktdetails anti-HIF3A Antikörper

Target: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIF3A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse HIF3 alpha

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:800-1:3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu HIF3A

Target: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Andere Bezeichnung: HIF3 alpha/IPAS (HIF3A Produkte)

Hintergrund: Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

Gen-ID: 53417

NCBI Accession: NP_001156422

UniProt: Q0VBL6

Pathways: Warburg Effekt