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HECTD1 Antikörper

HECTD1 Reaktivität: Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074186
  • Target Alle HECTD1 Antikörper anzeigen
    HECTD1 (HECT Domain Containing 1 (HECTD1))
    Reaktivität
    • 30
    • 19
    • 18
    • 2
    • 2
    • 2
    • 2
    Ratte
    Wirt
    • 25
    • 5
    Kaninchen
    Klonalität
    • 26
    • 4
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HECTD1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse HECTD1
  • Applikationshinweise
    IHC/IF (R) 1:1000-1:2000/1:1000-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    HECTD1 (HECT Domain Containing 1 (HECTD1))
    Andere Bezeichnung
    HECTD1 (HECTD1 Produkte)
    Synonyme
    RGD1561653 antikoerper, HECTD1 antikoerper, hectd1 antikoerper, MGC172681 antikoerper, A630086P08Rik antikoerper, AI844876 antikoerper, b2b327Clo antikoerper, opm antikoerper, HECT domain E3 ubiquitin protein ligase 1 antikoerper, HECT domain containing E3 ubiquitin protein ligase 1 antikoerper, Hectd1 antikoerper, HECTD1 antikoerper, hectd1 antikoerper
    Hintergrund
    HECTD1 (E3 ubiquitin-protein ligase, which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates . Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion . Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells impairs their emigration and is consequently essential for the correct development of the cranial neural folds and neural tube closure.It is also involved in sporadic Parkinson's disease.
    UniProt
    Q69ZR2
    Pathways
    Tube Formation, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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